Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607976 | 0.82 | MAPT (0.38) | MAPTRAB9AHTTSMN1; SMN2LPAR2 | |
| SCHEMBL8497061 | 0.82 | RAB9A (0.64) | MAPTRAB9AHTTSMN1; SMN2MEN1 | |
| SCHEMBL8496692 | 0.79 | PDE4A (0.53) | LDHA | |
| SCHEMBL8485494 | 0.79 | RPS6KB1 (0.47) | MAPTRAB9AHTTSMN1; SMN2MEN1 | |
| SCHEMBL30808068 | 0.79 | LDHA (0.46) | MAPTRAB9AHTTSMN1; SMN2LPAR2 | |
| SCHEMBL8484113 | 0.77 | HTT (0.42) | MAPTRAB9AHTTSMN1; SMN2MEN1 | |
| SCHEMBL8483456 | 0.76 | RXFP1 (0.42) | MAPTHTTSMN1; SMN2NR2F2KMT2A | |
| SCHEMBL9609202 | 0.75 | KMT2A (0.40) | RAB9AHTTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL9609199 | 0.75 | KMT2A (0.42) | RAB9AHTTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL8490055 | 0.74 | KMT2A (0.61) | RAB9AHTTSMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |