Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.47 |
| ▸ | AURKA | O14965 | 4/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609099 | 0.88 | RPS6KB1 (0.52) | RPS6KB1AURKALDHAPDPK1ALDH1A1 | |
| SCHEMBL8491743 | 0.87 | RPS6KB1 (0.46) | RPS6KB1AURKALDHAPDPK1ALDH1A1 | |
| SCHEMBL8504575 | 0.87 | RPS6KB1 (0.46) | RPS6KB1AURKALDHAPDPK1ALDH1A1 | |
| SCHEMBL8484113 | 0.86 | HTT (0.42) | LDHAALDH1A1KDM4EMAPK1TSHR | |
| SCHEMBL8490466 | 0.85 | RPS6KB1 (0.49) | RPS6KB1AURKALDHAPDPK1ALDH1A1 | |
| SCHEMBL8483456 | 0.84 | RXFP1 (0.42) | LDHAALDH1A1KDM4EMAPK1TSHR | |
| SCHEMBL9608188 | 0.82 | AURKA (0.42) | RPS6KB1AURKALDHAALDH1A1KDM4E | |
| SCHEMBL5569127 | 0.81 | MEN1 (0.48) | RPS6KB1AURKAALDH1A1KDM4EMAPK1 | |
| SCHEMBL8484236 | 0.80 | LDHA (0.46) | LDHAALDH1A1KDM4EMAPK1TSHR | |
| SCHEMBL8482247 | 0.79 | MAPT (0.42) | LDHAALDH1A1KDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |