Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8484742 | 0.82 | ALDH1A1 (0.48) | MEN1POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5862230 | 0.68 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL28217942 | 0.68 | SIGMAR1 (1.00) | SIGMAR1MEN1POLBKMT2AFAAH | |
| SCHEMBL29239819 | 0.67 | TSHR (0.53) | SIGMAR1MEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL7902716 | 0.67 | TP53 (0.60) | SIGMAR1TDP1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL23055097 | 0.66 | MAPT (0.59) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5862098 | 0.66 | SIGMAR1 (0.67) | SIGMAR1MEN1POLBKMT2AFAAH | |
| SCHEMBL11559495 | 0.66 | CYP2D6 (0.57) | SIGMAR1MEN1POLBKMT2AFAAH | |
| SCHEMBL10900487 | 0.66 | SIGMAR1 (0.66) | SIGMAR1POLBFAAH | |
| SCHEMBL3870604 | 0.65 | MCHR1 (0.73) | MEN1KMT2ASMN1; SMN2ALDH1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |