Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485627 | 0.93 | TOP2A (0.41) | TOP2ANQO1TOP2B | |
| SCHEMBL8487874 | 0.88 | NQO1 (0.35) | TOP2ANQO1TOP2B | |
| SCHEMBL10815656 | 0.88 | TOP2A (0.47) | TOP2ANQO1TOP2B | |
| SCHEMBL8489718 | 0.84 | NQO1 (0.35) | NQO1 | |
| SCHEMBL8486920 | 0.84 | TOP2A (0.43) | TOP2ATOP2B | |
| SCHEMBL8486344 | 0.82 | TOP2A (0.40) | TOP2A | |
| SCHEMBL8483753 | 0.82 | NQO1 (0.44) | TOP2ANQO1TOP2B | |
| SCHEMBL8487417 | 0.80 | TOP2A (0.44) | TOP2ANQO1TOP2B | |
| SCHEMBL8489284 | 0.80 | NQO1 (0.35) | TOP2ANQO1TOP2B | |
| SCHEMBL8483443 | 0.79 | TOP2A (0.43) | TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935969-A | Pyrido-thiopyrandoinazoles with antitumor activity | UNIVERSITY OF VERMONT (US) | 1999-08-10 | — | — | US | disclosed |