Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.49 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25796770 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBPKMCYP1A2 | |
| SCHEMBL21031716 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBPKMCYP1A2 | |
| SCHEMBL8103840 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MAPTPOLBPKMCYP1A2 | |
| SCHEMBL939398 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MAPTPOLBPKMCYP1A2 | |
| SCHEMBL23360737 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBPKMCYP1A2 | |
| SCHEMBL28418776 | 0.74 | MAPT (0.50) | ALDH1A1MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL23360716 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBPKMCYP1A2 | |
| SCHEMBL5236640 | 0.72 | MAPK1 (0.64) | ALDH1A1MAPTPKMCYP1A2CYP2C19 | |
| SCHEMBL1110499 | 0.72 | GAA (0.69) | ALDH1A1MAPTPKMCYP1A2CYP2C19 | |
| SCHEMBL22094803 | 0.72 | ALDH1A1 (0.68) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955460-A | EFFECTIVE AGAINST INFECTIONS CAUSED BY ANTIBIOTIC RESISTANT BACTERIA | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-21 | — | — | US | disclosed |
| US-5922707-A | Oxazolidinone antibacterial agent with tricyclic substituents | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-13 | — | — | US | disclosed |