Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.51 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.51 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104325 | 0.86 | CTSB (0.59) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL939398 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL21031716 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL25796770 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL8484094 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL28038606 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL28038246 | 0.75 | ALDH1A1 (0.69) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL4247986 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL23360737 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL1110499 | 0.74 | GAA (0.69) | ALDH1A1MAPTCYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743848-B1 | 2-FLUORO-6-NITROANILINES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |