Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.52 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.52 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22471527 | 0.87 | MAPT (0.54) | ALDH1A1MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL30464721 | 0.87 | MAPT (0.54) | ALDH1A1MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL21031716 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL8103840 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL939398 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL25796769 | 0.79 | HTT (0.49) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL8484094 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL23360737 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL19700166 | 0.77 | CTSB (0.55) | ALDH1A1MAPTPOLBCYP1A2CYP2C19 | |
| SCHEMBL1636077 | 0.76 | TDP1 (0.60) | ALDH1A1MAPTCYP1A2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691970-B2 | Pyrazolopyridinone compounds | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691970-B2 | Pyrazolopyridinone compounds | FGFR1, FGFR3, FGFR2 | ALDH1A1 1418/4885MAPT 1516/4885POLB 2610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.