Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486551 | 0.86 | PDE4B (0.47) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8601980 | 0.81 | BACE1 (0.42) | — | |
| SCHEMBL8484879 | 0.80 | PDE4B (0.44) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6584635 | 0.80 | PDE4B (0.48) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7174498 | 0.77 | PDE4B (0.48) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7170248 | 0.77 | PDE4B (0.48) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7170250 | 0.77 | PDE4B (0.48) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8486187 | 0.76 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL8486342 | 0.76 | PDE4B (0.46) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6584651 | 0.74 | PDE4B (0.57) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198919-B1 | PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | claimed |
| US-5998453-A | ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |
| US-5783591-A | Administration of oxazolidinone and pyrolidinone compounds for the treatment of inflammation | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |
| EP-0198919-B1 | PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0198919-A1 | PHARMACEUTICAL PREPARATIONS. | SCHERING AG (DE) | 1986-10-29 | — | — | EP | disclosed |
| WO-1986002268-A1 | PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1986-04-24 | — | — | WO | disclosed |