Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484115 | 0.81 | PDE4B (0.46) | — | |
| SCHEMBL8486551 | 0.66 | PDE4B (0.47) | — | |
| SCHEMBL20188810 | 0.65 | TLR4 (0.47) | BACE1ADAM17TLR4TLR2 | |
| SCHEMBL20201820 | 0.65 | ADAM17 (0.45) | BACE1ADAM17ACACBACACATLR4 | |
| SCHEMBL13647241 | 0.65 | ACACA (0.54) | ACACBACACATLR4TLR2 | |
| SCHEMBL17148210 | 0.65 | KDM4E (0.51) | ACACBACACAGRM2 | |
| SCHEMBL12696893 | 0.63 | TLR4 (0.45) | TLR4TLR2 | |
| SCHEMBL13859319 | 0.63 | BACE1 (0.44) | BACE1ADAM17TLR4TLR2 | |
| SCHEMBL12094236 | 0.63 | ACACA (0.49) | ACACBACACADUT | |
| SCHEMBL1409826 | 0.63 | ACACA (0.49) | ACACBACACADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783591-A | Administration of oxazolidinone and pyrolidinone compounds for the treatment of inflammation | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | claimed |
| EP-0198919-A1 | PHARMACEUTICAL PREPARATIONS. | SCHERING AG (DE) | 1986-10-29 | — | — | EP | claimed |
| WO-1986002268-A1 | PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1986-04-24 | — | — | WO | claimed |