Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602688 | 0.90 | MAPT (0.37) | MAPTTDP1ALDH1A1LMNAHPGD | |
| SCHEMBL9568932 | 0.86 | HPGD (0.35) | MAPTTDP1ALDH1A1LMNAHPGD | |
| SCHEMBL8602264 | 0.80 | ESR1 (0.35) | TDP1ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL9694976 | 0.80 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL8484124 | 0.80 | MAPK1 (0.31) | TDP1 | |
| SCHEMBL8603149 | 0.79 | MAPT (0.41) | MAPTTDP1ALDH1A1LMNAHPGD | |
| SCHEMBL8603206 | 0.78 | ESR1 (0.34) | TDP1ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL8603150 | 0.78 | ALDH1A1 (0.33) | MAPTALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL10578397 | 0.78 | PPOX (0.52) | MAPTTDP1ALDH1A1LMNAHPGD | |
| SCHEMBL8601360 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529402-A1 | N-(3-alkylthio-phenyl)-oxazindiones as herbicides | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |
| EP-0484776-A1 | Arylsubstituted alkyliden-nitrogenheterocycles | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |