SCHEMBL8484206

SCHEMBL8484206

CNC(=O)OC1CCc2c(cccc2OCC(=O)O)C1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 20/20 0.53
PTGDR Q13258 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8488192 0.90 MTNR1A (0.44) PTGIR
SCHEMBL8858465 0.79 PTGIR (0.64) PTGIRPTGDR
SCHEMBL8576529 0.78 MTNR1A (0.48) PTGIR
SCHEMBL8484202 0.78 CA1 (0.62) PTGIR
SCHEMBL7772422 0.77 PTGIR (0.60) PTGIR
SCHEMBL8858429 0.76 PTGIR (0.59) PTGIRPTGDR
SCHEMBL8414260 0.76 PTGIR (0.65) PTGIRPTGDR
SCHEMBL9049212 0.75 PTGIR (0.54) PTGIRPTGDR
SCHEMBL8858428 0.75 PTGIR (0.64) PTGIRPTGDR
SCHEMBL20476252 0.75 MTNR1A (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5863918-A HYPOTENSIVE AGENTS, ANTICOAGULANTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-01-26 US disclosed
US-5763489-A ANTICOAGULANTS AND HYPOTENSIVE AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-06-09 US disclosed