Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 12/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484206 | 0.90 | PTGIR (0.53) | PTGIR | |
| SCHEMBL8576529 | 0.89 | MTNR1A (0.48) | MTNR1AMTNR1BPTGIRDRD2DRD4 | |
| SCHEMBL9017314 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1BPTGIRDRD2DRD4 | |
| SCHEMBL9017305 | 0.80 | MTNR1A (0.48) | MTNR1AMTNR1BPTGIRDRD2DRD4 | |
| SCHEMBL8488188 | 0.80 | MTNR1A (0.60) | MTNR1AMTNR1BDRD2DRD4DRD3 | |
| SCHEMBL10464119 | 0.77 | MTNR1A (0.74) | MTNR1AMTNR1BDRD2DRD4DRD3 | |
| SCHEMBL8576525 | 0.77 | PTGIR (0.62) | PTGIR | |
| SCHEMBL8410514 | 0.77 | PTGIR (0.54) | MTNR1AMTNR1BPTGIR | |
| SCHEMBL9005627 | 0.76 | PTGIR (0.45) | MTNR1AMTNR1BPTGIRDRD2DRD4 | |
| SCHEMBL9005623 | 0.76 | PTGIR (0.45) | MTNR1AMTNR1BPTGIRDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |