Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TET3 | O43151 | 1/20 | 0.52 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.52 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8483231 | 0.99 | MCHR1 (0.53) | MCHR1MOKCDC7CDK19HPGD | |
| SCHEMBL8770308 | 0.95 | LMNA (0.52) | MCHR1MOKCDC7CDK19HPGD | |
| Hydrochloric Acid SCHEMBL8770318 | 0.94 | UTS2R (0.53) | MCHR1MOKCDC7CDK19HPGD | |
| SCHEMBL8481447 | 0.93 | KDM4E (0.61) | MCHR1HPGDKDM4ETET3TET2 | |
| Hydrochloric Acid SCHEMBL8481070 | 0.92 | KDM4E (0.60) | MCHR1HPGDKDM4ETET3TET2 | |
| SCHEMBL8481554 | 0.89 | CAMK2D (0.61) | MOKCAMK2DFYNRAD52 | |
| SCHEMBL8150809 | 0.88 | NPC1 (0.63) | MCHR1HPGDKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8480455 | 0.88 | CAMK2D (0.60) | MOKCAMK2DFYNRAD52 | |
| SCHEMBL8486450 | 0.82 | FYN (0.66) | HPGDKDM4ETET3TET2TET1 | |
| Hydrochloric Acid SCHEMBL8582820 | 0.81 | FYN (0.65) | HPGDKDM4ETET3TET2TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922743-A | USEFUL FOR AMELIORATION OF NERVE DISORDERS DUE TO NEURONAL DEGENERATION, SUCH AS INDUCED BY DRUGS OR ALCOHOL, INFLAMMATORY DISORDERS, DIABETES, ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, HUNTINGTON'S CHOREA, AND OTHERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0795545-A1 | PYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1997-09-17 | — | — | EP | disclosed |