Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480706 | 0.96 | MEN1 (0.41) | FASNMEN1KMT2APAK1GAA | |
| SCHEMBL8482088 | 0.83 | F3 (0.39) | PDE4DPDE4APDE4BPDE4CMEN1 | |
| SCHEMBL8484904 | 0.80 | PDE4D (0.33) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8485285 | 0.80 | F3 (0.42) | KDM4EALDH1A1GAA | |
| SCHEMBL8485766 | 0.79 | F3 (0.41) | — | |
| SCHEMBL8485301 | 0.78 | ALDH1A1 (0.35) | FASNKMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8483898 | 0.77 | DRD1 (0.37) | PDE4DPDE4BALDH1A1GAA | |
| SCHEMBL8480397 | 0.76 | PDE4B (0.38) | PDE4DPDE4BALDH1A1GAA | |
| SCHEMBL8487162 | 0.75 | F3 (0.38) | — | |
| SCHEMBL8484446 | 0.75 | PDE4B (0.39) | PDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922889-A | REACTING 3,7-DIMETHYL-6,8-DIMETHOXYISOCHROMAN WITH SODIUM ETHYL THIOLATE OR SODIUM HYDRIDE TO PRODUCE 3,7-DIMETHYL-6-HYDROXY-8-METHOXYISOCHROMAN; POSSESS PHYTOTOXIC ACTIVITY USED AS A BIODEGRADABLE HERBICIDE | THE UNITED STATES OD AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-07-13 | — | — | US | disclosed |