Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483878 | 0.99 | TOP2A (0.38) | F3TOP2AALOX15NLRP3CYP3A4 | |
| SCHEMBL8479256 | 0.99 | TOP2A (0.38) | F3TOP2AALOX15NLRP3CYP3A4 | |
| SCHEMBL8483098 | 0.99 | TOP2A (0.38) | F3TOP2AALOX15NLRP3CYP3A4 | |
| SCHEMBL8483236 | 0.93 | LMNA (0.36) | ALOX15NLRP3CYP3A4MAPK1CYP2C19 | |
| SCHEMBL8485285 | 0.92 | F3 (0.42) | F3TOP2AALOX15NLRP3CYP3A4 | |
| SCHEMBL8485869 | 0.91 | F3 (0.41) | F3TOP2ANLRP3CYP3A4MAPK1 | |
| SCHEMBL8485766 | 0.91 | F3 (0.41) | F3TOP2ANLRP3CYP3A4MAPK1 | |
| SCHEMBL8482088 | 0.88 | F3 (0.39) | F3TOP2ANLRP3CYP3A4MAPK1 | |
| SCHEMBL8485301 | 0.84 | ALDH1A1 (0.35) | F3NLRP3MTNR1B | |
| SCHEMBL8480861 | 0.81 | HTR2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922889-A | REACTING 3,7-DIMETHYL-6,8-DIMETHOXYISOCHROMAN WITH SODIUM ETHYL THIOLATE OR SODIUM HYDRIDE TO PRODUCE 3,7-DIMETHYL-6-HYDROXY-8-METHOXYISOCHROMAN; POSSESS PHYTOTOXIC ACTIVITY USED AS A BIODEGRADABLE HERBICIDE | THE UNITED STATES OD AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-07-13 | — | — | US | claimed |
| US-5922889-A | REACTING 3,7-DIMETHYL-6,8-DIMETHOXYISOCHROMAN WITH SODIUM ETHYL THIOLATE OR SODIUM HYDRIDE TO PRODUCE 3,7-DIMETHYL-6-HYDROXY-8-METHOXYISOCHROMAN; POSSESS PHYTOTOXIC ACTIVITY USED AS A BIODEGRADABLE HERBICIDE | THE UNITED STATES OD AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1999-07-13 | — | — | US | disclosed |