SCHEMBL8484389

SCHEMBL8484389

Clc1cccc(Cl)c1SC(Cl)Cl.Sc1c(Cl)cccc1Cl

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
NR4A2 P43354 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9018802 0.89 CYP1A2 (0.39) CYP1A2CYP2A6TSHRLMNANR4A2
SCHEMBL190658 0.76
SCHEMBL8487863 0.74 CYP1A2 (0.35) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL27928635 0.74 CYP2A6 (0.47) CYP1A2CYP2A6TSHRLMNANR4A2
SCHEMBL1968215 0.69
SCHEMBL13816926 0.69 CYP1A2 (0.38) CYP1A2CYP2A6TSHRLMNANR4A2
SCHEMBL3658340 0.66
SCHEMBL8488464 0.65 LMNA (0.35) TSHRLMNAALDH1A1
SCHEMBL10378510 0.64 CYP1A2 (0.43) CYP1A2CYP2A6TSHRLMNANR4A2
Hydrochloric Acid SCHEMBL2001788 0.64 TSHR (0.52) CYP1A2CYP2A6TSHRLMNANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed