Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485533 | 0.98 | NPSR1 (0.42) | NPSR1DRD2DRD3CKS1BSKP1 | |
| SCHEMBL8666092 | 0.95 | UTS2R (0.39) | NPSR1DRD2CKS1BSKP1SKP2 | |
| SCHEMBL8665880 | 0.93 | UTS2R (0.39) | NPSR1DRD2CKS1BSKP1SKP2 | |
| SCHEMBL8501048 | 0.92 | NPSR1 (0.35) | NPSR1UTS2RSCN9AHTR2A | |
| SCHEMBL8501233 | 0.90 | NPSR1 (0.36) | NPSR1DRD2DRD3UTS2RSCN9A | |
| SCHEMBL8712537 | 0.89 | CCR3 (0.43) | NPSR1DRD2KMT2AMEN1CCR3 | |
| SCHEMBL8717870 | 0.88 | NPSR1 (0.38) | NPSR1DRD2DRD3CKS1BSKP1 | |
| SCHEMBL8713180 | 0.87 | CKS1B (0.41) | DRD2CKS1BSKP1SKP2MCHR1 | |
| SCHEMBL8717983 | 0.87 | CCR3 (0.43) | NPSR1DRD2KMT2AMEN1CCR3 | |
| SCHEMBL8483684 | 0.86 | NPSR1 (0.41) | NPSR1DRD2DRD3CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |