Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665477 | 0.95 | DRD2 (0.37) | NPSR1MCHR1DRD2SCN1ASCN5A | |
| SCHEMBL8524381 | 0.89 | CCR3 (0.42) | NPSR1DRD2CCR3SLC6A12KMT2A | |
| SCHEMBL8485533 | 0.89 | NPSR1 (0.42) | NPSR1MCHR1DRD2DRD3SCN1A | |
| SCHEMBL8484454 | 0.88 | NPSR1 (0.42) | NPSR1MCHR1DRD2DRD3SCN1A | |
| SCHEMBL8666998 | 0.85 | CCR3 (0.40) | DRD2CCR3SLC6A12KMT2AMEN1 | |
| SCHEMBL8665880 | 0.84 | UTS2R (0.39) | NPSR1MCHR1DRD2CKS1BSKP1 | |
| SCHEMBL8666092 | 0.84 | UTS2R (0.39) | NPSR1MCHR1DRD2CKS1BSKP1 | |
| SCHEMBL8501233 | 0.81 | NPSR1 (0.36) | NPSR1DRD2DRD3SCN9AHTR2A | |
| SCHEMBL8501048 | 0.80 | NPSR1 (0.35) | NPSR1SCN9AHTR2A | |
| SCHEMBL8717983 | 0.78 | CCR3 (0.43) | NPSR1DRD2CCR3SLC6A12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |