Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664869 | 0.95 | SMPD3 (0.38) | CKS1BSKP1SKP2 | |
| SCHEMBL8485533 | 0.89 | NPSR1 (0.42) | CKS1BSKP1SKP2CNR1CNR2 | |
| SCHEMBL8717983 | 0.88 | CCR3 (0.43) | ALDH1A1CNR1CNR2DRD2 | |
| SCHEMBL8484454 | 0.87 | NPSR1 (0.42) | CKS1BSKP1SKP2CNR1CNR2 | |
| SCHEMBL8712537 | 0.85 | CCR3 (0.43) | CNR1CNR2DRD2 | |
| SCHEMBL8712879 | 0.85 | HTR1A (0.37) | ALDH1A1DRD2 | |
| SCHEMBL8665880 | 0.85 | UTS2R (0.39) | CKS1BSKP1SKP2DRD2MCHR1 | |
| SCHEMBL8593677 | 0.83 | ALDH1A1 (0.36) | ALDH1A1RAB9ADRD2 | |
| SCHEMBL8665515 | 0.83 | CCR3 (0.41) | DRD2 | |
| SCHEMBL8648475 | 0.83 | CCR3 (0.39) | ALDH1A1CNR1CNR2DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |