Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501233 | 0.98 | NPSR1 (0.36) | NPSR1UTS2RHPGDKCNH2SCN9A | |
| SCHEMBL8666092 | 0.94 | UTS2R (0.39) | NPSR1UTS2RCHRM1 | |
| SCHEMBL8484454 | 0.92 | NPSR1 (0.42) | NPSR1UTS2RSCN9AHTR2A | |
| SCHEMBL8665880 | 0.91 | UTS2R (0.39) | NPSR1UTS2RCHRM1 | |
| SCHEMBL8485533 | 0.90 | NPSR1 (0.42) | NPSR1UTS2RSCN9AHTR2A | |
| SCHEMBL8502237 | 0.88 | NPSR1 (0.38) | NPSR1UTS2RHPGDKCNH2SCN9A | |
| SCHEMBL8500996 | 0.86 | CTSL (0.37) | NAAAHTR2A | |
| SCHEMBL8504375 | 0.85 | CCR3 (0.38) | NPSR1UTS2R | |
| SCHEMBL8665525 | 0.83 | CCR3 (0.40) | NPSR1 | |
| SCHEMBL8669685 | 0.82 | NPSR1 (0.42) | NPSR1UTS2RCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | claimed |
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |