Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484117 | 0.95 | ACHE (0.57) | ACHEKDM4EALDH1A1MAPTHIF1A | |
| SCHEMBL8481052 | 0.79 | KMT2A (0.43) | KDM4EALDH1A1MAPTHIF1AHRH3 | |
| SCHEMBL8483277 | 0.76 | KMT2A (0.45) | KDM4EALDH1A1MAPTHIF1AHRH3 | |
| SCHEMBL8483963 | 0.76 | ACHE (0.57) | ACHEKDM4EALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL13812393 | 0.76 | ACHE (0.57) | ACHEKDM4EALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL8483969 | 0.76 | ACHE (0.57) | ACHEKDM4EALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL8484583 | 0.74 | KMT2A (0.42) | KDM4EALDH1A1MAPTHIF1AHRH3 | |
| SCHEMBL3594265 | 0.73 | ALDH1A1 (0.56) | ACHEKDM4EALDH1A1HRH3CHRM1 | |
| SCHEMBL8480820 | 0.73 | CHRM4 (0.60) | ACHEKDM4EALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL9058966 | 0.73 | ACHE (0.60) | ACHEKDM4EALDH1A1MAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |