Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.74 |
| ▸ | MMP3 | P08254 | 13/20 | 0.74 |
| ▸ | MMP2 | P08253 | 8/20 | 0.74 |
| ▸ | MMP9 | P14780 | 6/20 | 0.74 |
| ▸ | MMP8 | P22894 | 6/20 | 0.74 |
| ▸ | MMP7 | P09237 | 4/20 | 0.74 |
| ▸ | MMP13 | P45452 | 1/20 | 0.74 |
| ▸ | FCER2 | P06734 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487985 | 0.95 | MMP1 (0.79) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8484262 | 0.95 | MMP1 (0.75) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8484818 | 0.94 | MMP3 (0.80) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8486757 | 0.91 | MMP1 (0.70) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8481866 | 0.90 | MMP3 (0.75) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8482048 | 0.90 | MMP3 (0.84) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8481745 | 0.89 | MMP2 (0.73) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8484210 | 0.89 | MMP3 (0.89) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8484275 | 0.87 | MMP3 (0.79) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8485227 | 0.85 | MMP2 (0.67) | MMP1MMP3MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990158-A | EXTRACELLULAR MATRIX METALLOPROTEINASES INHIBITORS; ORAL ADMINISTRATION; BIOAVAILABILITY; E.G.,N-(2-(2'-(5-METHYL-2-OXO-1,3-DIOXOL-4-YL)METHYLENE-OXY-2'-OXO-ETHYL)-5 -(4-METH-OXYPHENYL)OXY)PENTANOYL)PHENYLALANINE N-METHYLAMIDE | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |