Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488939 | 0.92 | NAMPT (0.35) | NAMPTALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8488363 | 0.91 | NAMPT (0.38) | NAMPTALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL8488436 | 0.90 | NAMPT (0.40) | NAMPTALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8486426 | 0.88 | NAMPT (0.41) | NAMPTALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8489290 | 0.81 | KMT2A (0.36) | NAMPTALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL8488439 | 0.81 | NAMPT (0.43) | NAMPTALDH1A1MAPTSMN1; SMN2KMT2A | |
| Benzoic Acid SCHEMBL8489705 | 0.78 | ALDH1A1 (0.40) | NAMPTALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8489699 | 0.77 | ALDH1A1 (0.37) | NAMPTALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8488725 | 0.76 | MAPT (0.38) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL8489042 | 0.75 | GAA (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955463-A | ANTITUMOR, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |