Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478242 | 0.79 | POLB (0.41) | POLBTDP1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL6585844 | 0.78 | TRPV1 (0.36) | DRD2SMN1; SMN2 | |
| SCHEMBL9785817 | 0.77 | POLB (0.44) | POLBCHRM4DRD2HTR7KDM4E | |
| SCHEMBL30812977 | 0.77 | POLB (0.44) | POLBCHRM4DRD2HTR7KDM4E | |
| SCHEMBL11084894 | 0.75 | S1PR1 (0.40) | POLBCHRM4DRD2HTR7SMN1; SMN2 | |
| SCHEMBL6585849 | 0.74 | BRD4 (0.40) | — | |
| SCHEMBL30168994 | 0.73 | P2RX7 (0.46) | — | |
| SCHEMBL6583942 | 0.73 | NOTUM (0.36) | CHRM4DRD2HTR7ACHEBCHE | |
| SCHEMBL8563821 | 0.72 | HTR1A (0.35) | DRD2ACHE | |
| SCHEMBL9976868 | 0.71 | POLB (0.55) | POLBCHRM4DRD2HTR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968954-A | EXHIBIT SELECTIVE BINDING AFFINITY FOR 5-HYDROXYTRYPTAMINE RECEPTORS | ADIR ET COMPAGNIE (FR) | 1999-10-19 | — | — | US | disclosed |