Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779828 | 0.88 | TSHR (0.43) | LMNATSHRHAO1ALDH1A1KDM4E | |
| SCHEMBL8487569 | 0.76 | MAPT (0.40) | LMNATSHRHAO1ALDH1A1KDM4E | |
| SCHEMBL48322 | 0.76 | — | — | |
| SCHEMBL29565928 | 0.76 | — | — | |
| SCHEMBL8488464 | 0.74 | LMNA (0.35) | LMNATSHRHAO1ALDH1A1KDM4E | |
| Hydrogen Sulfide SCHEMBL27747337 | 0.73 | TSHR (0.53) | LMNATSHRALDH1A1MAPTCYP2A6 | |
| SCHEMBL28074146 | 0.73 | — | — | |
| Hydrogen Sulfide SCHEMBL28264855 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7262825 | 0.73 | — | — | |
| SCHEMBL1855522 | 0.71 | TSHR (0.39) | LMNATSHRALDH1A1MAPTCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932731-A | HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |