Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485779 | 0.88 | LMNA (0.33) | TSHRLMNAHAO1CYP2A6RHEB | |
| SCHEMBL1855522 | 0.81 | TSHR (0.39) | TSHRLMNACYP2A6IDO1ALDH1A1 | |
| SCHEMBL10503312 | 0.78 | TSHR (0.41) | TSHRLMNAHAO1RHEBFBP1 | |
| SCHEMBL7111480 | 0.78 | LMNA (0.41) | TSHRLMNAHAO1RHEBFBP1 | |
| SCHEMBL30165577 | 0.78 | TSHR (0.41) | TSHRLMNAHAO1RHEBFBP1 | |
| SCHEMBL30053659 | 0.78 | LMNA (0.41) | TSHRLMNAHAO1RHEBFBP1 | |
| SCHEMBL6915666 | 0.73 | RHEB (0.55) | TSHRLMNAHAO1RHEBFBP1 | |
| SCHEMBL225608 | 0.73 | FBP1 (0.55) | TSHRLMNAHAO1CYP2A6RHEB | |
| SCHEMBL31464849 | 0.73 | FBP1 (0.55) | TSHRLMNAHAO1CYP2A6RHEB | |
| SCHEMBL29543966 | 0.73 | RHEB (0.55) | TSHRLMNAHAO1RHEBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770599-A1 | PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |
| EP-0742201-A1 | PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |