Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8489957 | 0.98 | REN (0.32) | RENDYRK1APIK3CAMTORBACE1 | |
| SCHEMBL1719712 | 0.77 | BACE1 (0.47) | RENBACE1 | |
| SCHEMBL4872319 | 0.71 | DYRK1A (0.33) | RENDYRK1APIK3CAMTORMAPK1 | |
| SCHEMBL4840039 | 0.65 | DYRK1A (0.35) | DYRK1APIK3CAMTORMAPK1RIPK1 | |
| SCHEMBL29421618 | 0.65 | PDPK1 (0.44) | RENDYRK1APDPK1 | |
| SCHEMBL17223741 | 0.65 | PDPK1 (0.44) | RENDYRK1APDPK1 | |
| SCHEMBL31078356 | 0.65 | DYRK1A (0.40) | DYRK1APIK3CAMTORBACE1ALOX15 | |
| SCHEMBL11343722 | 0.64 | NR4A2 (0.50) | BACE1HTTALOX15MAPK1 | |
| SCHEMBL482375 | 0.64 | BACE1 (0.60) | BACE1GAATSHRHTT | |
| SCHEMBL31667822 | 0.64 | BACE1 (0.60) | BACE1GAATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999025708-A1 | PYRROLO[3,2-b]PYRIDINE PROCESSES AND INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | claimed |