Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387544 | 0.83 | ALDH1A1 (0.44) | SIGMAR1DDB1CRBNALDH1A1THRB | |
| SCHEMBL1387541 | 0.83 | ALDH1A1 (0.44) | SIGMAR1DDB1CRBNALDH1A1THRB | |
| SCHEMBL1387543 | 0.83 | ALDH1A1 (0.44) | SIGMAR1DDB1CRBNALDH1A1THRB | |
| SCHEMBL8400979 | 0.81 | DDB1 (0.45) | SIGMAR1IDO1DDB1CRBNTDO2 | |
| SCHEMBL9041157 | 0.81 | DDB1 (0.41) | SIGMAR1IDO1DDB1CRBNTDO2 | |
| SCHEMBL4988928 | 0.79 | IDO1 (0.46) | IDO1TDO2GSK3BALDH1A1KDM4E | |
| SCHEMBL8488166 | 0.76 | IDO1 (0.38) | IDO1TDO2GSK3BALDH1A1KDM4E | |
| SCHEMBL8488172 | 0.76 | IDO1 (0.38) | IDO1TDO2GSK3BALDH1A1KDM4E | |
| SCHEMBL8488163 | 0.76 | IDO1 (0.38) | IDO1TDO2GSK3BALDH1A1KDM4E | |
| SCHEMBL31728057 | 0.74 | IDO1 (0.51) | IDO1TDO2GSK3BALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977355-A | Processes and intermediates for preparing 3-amino-benzo(b)azepinones | PFIZER INC. (US) | 1999-11-02 | — | — | US | disclosed |