Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FER | P16591 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488166 | 1.00 | IDO1 (0.38) | IDO1GSK3BTDO2CCKBRBRPF1 | |
| SCHEMBL8488163 | 1.00 | IDO1 (0.38) | IDO1GSK3BTDO2CCKBRBRPF1 | |
| SCHEMBL8486117 | 0.76 | SIGMAR1 (0.44) | IDO1GSK3BTDO2ALDH1A1KDM4E | |
| SCHEMBL4988928 | 0.73 | IDO1 (0.46) | IDO1GSK3BTDO2BRPF1CREBBP | |
| SCHEMBL3157916 | 0.69 | IDO1 (0.45) | IDO1GSK3BTDO2CCKBRBRPF1 | |
| SCHEMBL4115729 | 0.69 | IDO1 (0.45) | IDO1GSK3BTDO2CCKBRBRPF1 | |
| SCHEMBL3163873 | 0.69 | IDO1 (0.45) | IDO1GSK3BTDO2CCKBRBRPF1 | |
| SCHEMBL7819792 | 0.68 | S100A4 (0.42) | IDO1BRPF1CREBBPMAOAMAOB | |
| SCHEMBL136975 | 0.68 | IDO1 (0.40) | IDO1GSK3BTDO2BRPF1CREBBP | |
| SCHEMBL1387541 | 0.67 | ALDH1A1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977355-A | Processes and intermediates for preparing 3-amino-benzo(b)azepinones | PFIZER INC. (US) | 1999-11-02 | — | — | US | disclosed |