Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | S100A4 | P26447 | 3/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535923 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1HPRT1TSHRLMNA | |
| SCHEMBL9824568 | 0.81 | GPR35 (0.51) | ALDH1A1TDP1HPRT1TSHRS100A4 | |
| SCHEMBL3541396 | 0.73 | ALDH1A1 (0.71) | ALDH1A1TDP1TSHRS100A4GPR35 | |
| SCHEMBL1767571 | 0.71 | ALDH1A1 (0.63) | ALDH1A1TDP1HPRT1TSHRS100A4 | |
| SCHEMBL3538629 | 0.71 | TDP1 (0.58) | ALDH1A1TDP1TSHRS100A4GPR35 | |
| Water SCHEMBL11552278 | 0.68 | ALDH1A1 (0.69) | ALDH1A1TDP1HPRT1TSHRS100A4 | |
| SCHEMBL3937758 | 0.67 | TSHR (0.61) | ALDH1A1TDP1TSHRS100A4GPR35 | |
| SCHEMBL6396044 | 0.67 | ALDH1A1 (0.57) | ALDH1A1TDP1HPRT1S100A4LMNA | |
| SCHEMBL10453012 | 0.67 | ALDH1A1 (0.52) | ALDH1A1TDP1HPRT1S100A4LMNA | |
| SCHEMBL11339777 | 0.66 | ALDH1A1 (0.75) | ALDH1A1TDP1TSHRGPR35CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939418-A | ANTICOAGULANT | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-08-17 | — | — | US | disclosed |