Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485189 | 0.85 | TP53 (0.48) | ALDH1A1CA1CA2CA9CHRM1 | |
| SCHEMBL8485554 | 0.84 | QPCT (0.63) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL8488739 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL8483983 | 0.78 | CYP2D6 (0.55) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL8484029 | 0.78 | CYP2D6 (0.54) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL8483565 | 0.77 | TSHR (0.54) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL8482499 | 0.76 | CYP2D6 (0.67) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL8488067 | 0.76 | CA1 (0.49) | CA1CA2CA9CYP3A4CYP2D6 | |
| SCHEMBL8795185 | 0.75 | MEN1 (0.61) | ALDH1A1CA1CA2CA9CYP3A4 | |
| SCHEMBL8487591 | 0.75 | ALDH1A1 (0.57) | ALDH1A1CA1CA2CA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |