SCHEMBL8486708

SCHEMBL8486708

Cn1[nH]c(=O)n(Cc2cccc(Br)c2)c1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.49
HPGD P15428 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HIF1A Q16665 1/20 0.48
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
LMNA P02545 4/20 0.44
TSHR P16473 4/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
CYP11B1 P15538 1/20 0.42
ADRA2C P18825 1/20 0.42
CYP11B2 P19099 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
BRAF P15056 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 2/20 0.42
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783979 0.82 MAPT (0.49) HPGDLMNAL3MBTL1KMT2AMEN1
SCHEMBL19783871 0.81 GSK3B (0.51) HPGDALDH1A1TSHRL3MBTL1KMT2A
SCHEMBL19783302 0.73 MEN1 (0.47) MAPK1HPGDALDH1A1LMNATSHR
SCHEMBL23003843 0.71 SMN1; SMN2 (0.51) MAPK1HPGDALDH1A1HIF1ALMNA
SCHEMBL7672546 0.70 MAPT (0.52) MAPK1HPGDALDH1A1HIF1AERCC5
SCHEMBL7660286 0.70 MAPT (0.46) MAPK1HPGDALDH1A1HIF1ALMNA
SCHEMBL5201520 0.69 ALDH1A1 (0.55) ALDH1A1HIF1ATSHRL3MBTL1KMT2A
SCHEMBL16029477 0.68 KMT2A (0.60) MAPK1HPGDALDH1A1HIF1ALMNA
SCHEMBL16029357 0.67 SMN1; SMN2 (0.73) MAPK1HPGDALDH1A1HIF1ALMNA
SCHEMBL19784136 0.67 KMT2A (0.57) ALDH1A1LMNATSHRL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484877-B1 BICYCLIC COMPOUNDS AS PEST CONTROLLERS BAYER CROPSCIENCE AG (DE) 2020-07-01 EP disclosed
US-20190297887-A1 BICYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-10-03 US disclosed
WO-1999007687-A1 PESTICIDAL 4-BENZYL-1,2,4-TRIAZOLIN-5-ONE DERIVATIVES AGREVO UK LIMITED (GB) 1999-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190297887-A1 BICYCLIC COMPOUNDS AS PESTICIDES DDT, BCHE, ACHE MAPK1 4333/4885HPGD 1970/4885ALDH1A1 3199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.