Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664821 | 0.81 | FAAH (0.52) | PIK3R1PIK3CAMAPK1ALDH1A1HIF1A | |
| SCHEMBL7671570 | 0.79 | PIK3R1 (0.38) | MAPTPIK3R1PIK3CAMAPK1ALDH1A1 | |
| SCHEMBL7672546 | 0.77 | MAPT (0.52) | MAPTMAPK1HPGDALDH1A1HIF1A | |
| SCHEMBL7671137 | 0.77 | TLR7 (0.41) | MAPTPIK3R1PIK3CAALDH1A1MEN1 | |
| SCHEMBL8486708 | 0.70 | MAPK1 (0.49) | MAPTMAPK1HPGDALDH1A1HIF1A | |
| SCHEMBL15825630 | 0.69 | ALDH1A1 (0.43) | MAPK1ALDH1A1POLBADORA1 | |
| SCHEMBL3981770 | 0.69 | IDO1 (0.46) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL7666649 | 0.68 | CHEK1 (0.39) | MAPTHPGDALDH1A1 | |
| SCHEMBL8768659 | 0.68 | KDM4E (0.35) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30626656 | 0.68 | IDO1 (0.50) | MAPK1MEN1KMT2APOLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |