Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537617 | 0.80 | KMT2A (0.44) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4537616 | 0.80 | KMT2A (0.44) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8015200 | 0.80 | KDM4E (0.38) | NOTUMCRHR1KMT2AL3MBTL1KDM4E | |
| SCHEMBL2895077 | 0.74 | MEN1 (0.41) | KMT2AKDM4EALDH1A1GAACASP3 | |
| SCHEMBL30783064 | 0.74 | MEN1 (0.41) | KMT2AKDM4EALDH1A1GAACASP3 | |
| SCHEMBL8018603 | 0.71 | LMNA (0.45) | KMT2AL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL8018607 | 0.71 | LMNA (0.45) | KMT2AL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL16953233 | 0.71 | TRPA1 (0.36) | KDM4EALDH1A1GAACASP3SENP8 | |
| SCHEMBL31251566 | 0.70 | SMN1; SMN2 (0.38) | KMT2AL3MBTL1ALDH1A1GAATRPA1 | |
| SCHEMBL15547200 | 0.70 | CA1 (0.46) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716081-B1 | Highly selective process for the preparation of enantiomerically pure phenyl-substituted 1,4-dihydropyridine-3,5-dicarboxylic acid derivatives | BAYER HEALTHCARE AG (DE) | 2006-04-05 | — | — | EP | disclosed |