Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
| ▸ | HTR1B | P28222 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11394252 | 0.93 | LMNA (0.66) | HTR1DHTR1BSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8393097 | 0.84 | GAA (0.61) | HTR1DHTR1BSMN1; SMN2LMNATSHR | |
| SCHEMBL11735898 | 0.83 | ALDH1A1 (0.62) | HTR1DHTR1BSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8706674 | 0.83 | MEN1 (0.64) | HTR1DHTR1BTSHRATMMEN1 | |
| Hydrochloric Acid SCHEMBL8392166 | 0.82 | MEN1 (0.62) | HTR1DHTR1BTSHRATMMEN1 | |
| SCHEMBL8699166 | 0.81 | HTR1D (0.57) | HTR1DHTR1BSMN1; SMN2LMNATSHR | |
| SCHEMBL4888000 | 0.81 | ALDH1A1 (0.69) | HTR1BSMN1; SMN2ALDH1A1HPGDHTT | |
| SCHEMBL28086775 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1HPGDHTTLMNA | |
| Hydrochloric Acid SCHEMBL6561435 | 0.80 | ALDH1A1 (0.67) | HTR1BSMN1; SMN2ALDH1A1HPGDHTT | |
| SCHEMBL3888894 | 0.79 | LMNA (0.86) | HTR1DHTR1BSMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |