Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705093 | 0.83 | HTR1D (0.53) | HTR1DHTR1BATMHTR6LMNA | |
| SCHEMBL8487152 | 0.81 | HTR1D (0.62) | HTR1DHTR1BATMHTR6LMNA | |
| SCHEMBL8392079 | 0.80 | HTR1D (0.60) | HTR1DHTR1BATMHTR6LMNA | |
| SCHEMBL8392132 | 0.79 | HTR1D (0.59) | HTR1DHTR1BATMHTR6LMNA | |
| Hydrochloric Acid SCHEMBL8743607 | 0.79 | HTR1D (0.59) | HTR1DHTR1BATMHTR6LMNA | |
| SCHEMBL8389644 | 0.78 | HTR1D (0.57) | HTR1DHTR1BATMHTR6LMNA | |
| SCHEMBL8393097 | 0.78 | GAA (0.61) | HTR1DHTR1BATMLMNAKDM4E | |
| SCHEMBL4611512 | 0.77 | NPC1 (0.57) | MAPTMAPK1L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL8699161 | 0.75 | RAB9A (0.40) | ATMLMNAKDM4EMAPTTSHR | |
| SCHEMBL11394252 | 0.75 | LMNA (0.66) | HTR1DHTR1BATMLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |