Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910347 | 0.99 | KDM4E (0.33) | KDM4E | |
| SCHEMBL9080766 | 0.91 | OPRM1 (0.34) | — | |
| SCHEMBL8806112 | 0.91 | — | — | |
| SCHEMBL9080460 | 0.90 | LTB4R2 (0.34) | — | |
| SCHEMBL9081221 | 0.90 | — | — | |
| SCHEMBL8808317 | 0.90 | — | — | |
| SCHEMBL8486859 | 0.89 | LTB4R2 (0.34) | — | |
| SCHEMBL8486836 | 0.89 | AGTR1 (0.33) | — | |
| SCHEMBL8488532 | 0.89 | AGTR1 (0.37) | — | |
| SCHEMBL8489272 | 0.89 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955487-A | TREATING HIGH BLOOD PRESSURE, CARDIAC INSUFFICIENCY, GLAUCOMA | CIBA-GEIGY CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |