Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486859 | 0.99 | LTB4R2 (0.34) | LTB4R2USP2ALDH1A1LMNAPKM | |
| SCHEMBL8488532 | 0.95 | AGTR1 (0.37) | LTB4R2PKMAGTR1PTGDR2 | |
| SCHEMBL8483534 | 0.95 | LTB4R2 (0.37) | LTB4R2PKMAGTR1PTGDR2 | |
| SCHEMBL9079124 | 0.94 | LTB4R2 (0.36) | LTB4R2PKMAGTR1PTGDR2 | |
| SCHEMBL9080766 | 0.93 | OPRM1 (0.34) | LTB4R2 | |
| SCHEMBL8487185 | 0.90 | KDM4E (0.33) | — | |
| SCHEMBL8807760 | 0.90 | USP2 (0.32) | LTB4R2USP2ALDH1A1LMNAPKM | |
| SCHEMBL8910347 | 0.89 | KDM4E (0.33) | — | |
| SCHEMBL8808240 | 0.89 | USP2 (0.33) | LTB4R2USP2ALDH1A1LMNAPKM | |
| SCHEMBL9080394 | 0.89 | LTB4R2 (0.34) | LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |