Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483346 | 0.88 | MMP9 (0.63) | MMP9MMP8TACR1MMP2MEN1 | |
| SCHEMBL8198380 | 0.83 | MMP9 (0.63) | HTR2AMMP9MMP8HTR2CTACR1 | |
| SCHEMBL8198377 | 0.83 | MMP9 (0.63) | HTR2AMMP9MMP8HTR2CTACR1 | |
| SCHEMBL28822903 | 0.79 | HTR2A (0.64) | HTR2AHTR2CNOTUMMPOTSHR | |
| SCHEMBL28504603 | 0.79 | HTR2A (0.64) | HTR2AHTR2CNOTUMMPOTSHR | |
| SCHEMBL28504602 | 0.79 | HTR2A (0.64) | HTR2AHTR2CNOTUMMPOTSHR | |
| SCHEMBL8481416 | 0.77 | MMP9 (0.62) | MMP9MMP8TACR1MMP2MEN1 | |
| SCHEMBL8850751 | 0.73 | MMP9 (0.60) | MMP9MMP8TACR1MMP2MEN1 | |
| SCHEMBL8850747 | 0.73 | MMP9 (0.60) | MMP9MMP8TACR1MMP2MEN1 | |
| SCHEMBL21292855 | 0.73 | HTR2A (0.61) | HTR2AHTR2CNOTUMMPOTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856354-A | RESPIRATORY SYSTEM DISORDERS, ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL DISORDERS, VISION DEFECTS, ANTIALLERGENS,PAIN, NERVOUS SYSTEM DISORDERS, HEADACHES | WARNER-LAMBERT COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| US-5716979-A | NONPEPTIDES, UNIQUE IN ALKYLATION/SUBSTITUTION PATTERN ALONG THEIR BACKBONE, USEFUL FOR TREATING DISORDERS SUCH AS RESPIRATORY, INFLAMMATORY, GASTROINTESTINAL, OPHTHALMIC, ALLERGIES, PAIN, VASCULAR, MIGRANE, ARTHRITIS AND BRAIN | WARNER-LAMBERT COMPANY (US) | 1998-02-10 | — | — | US | disclosed |