Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152686 | 0.81 | DYRK1A (0.50) | CA12CA2 | |
| SCHEMBL6737344 | 0.80 | CA2 (0.51) | PTGS2CA12CA2 | |
| SCHEMBL165069 | 0.79 | CA2 (0.57) | PTGS2CA12CA2 | |
| SCHEMBL8487656 | 0.79 | PTGS2 (0.75) | PTGS2CA2 | |
| SCHEMBL8486090 | 0.74 | PTGS2 (0.62) | PTGS2CA2 | |
| SCHEMBL6725806 | 0.74 | PTGS2 (0.75) | PTGS2 | |
| SCHEMBL5502727 | 0.74 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL15562888 | 0.72 | ALDH1A1 (0.51) | CA12CA2 | |
| Hydrogen Sulfide SCHEMBL27744400 | 0.72 | PTGS2 (0.96) | PTGS2 | |
| SCHEMBL6728822 | 0.72 | PTGS2 (0.71) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | disclosed |