Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487208 | 0.78 | MEN1 (0.47) | HSD17B10TSHRLMNAALDH1A1FAAH | |
| SCHEMBL8491628 | 0.77 | CYP2D6 (0.48) | LMNAALDH1A1FAAHKMT2AMEN1 | |
| SCHEMBL1223807 | 0.75 | RAB9A (0.67) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL4884973 | 0.74 | LMNA (0.54) | HSD17B10LMNAALDH1A1FAAHKMT2A | |
| SCHEMBL14197151 | 0.74 | LMNA (0.54) | HSD17B10LMNAALDH1A1FAAHKMT2A | |
| SCHEMBL31043866 | 0.74 | HIF1A (0.53) | HSD17B10LMNAALDH1A1FAAHKMT2A | |
| SCHEMBL8491622 | 0.73 | CYP2D6 (0.49) | HSD17B10TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL31044025 | 0.73 | MAPT (0.59) | HSD17B10TSHRLMNAALDH1A1FAAH | |
| SCHEMBL31043824 | 0.73 | LMNA (0.57) | HSD17B10LMNAALDH1A1FAAHKMT2A | |
| SCHEMBL13033243 | 0.73 | SMN1; SMN2 (0.72) | HSD17B10TSHRLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |