Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487873 | 0.86 | DRD2 (0.46) | HTR1ADRD2HTR6POLBHTR7 | |
| SCHEMBL8485597 | 0.83 | MAPK1 (0.52) | DRD2HTR7DRD3DRD4KDM4E | |
| SCHEMBL7372124 | 0.75 | HTR6 (0.43) | HTR1ADRD2HTR6POLBHTR7 | |
| SCHEMBL7373095 | 0.73 | MAPK1 (0.46) | DRD2POLBHTR7DRD3DRD4 | |
| SCHEMBL7372515 | 0.71 | MAPK1 (0.44) | DRD2POLBHTR7DRD3DRD4 | |
| SCHEMBL7366955 | 0.70 | HTR6 (0.43) | HTR1ADRD2HTR6POLBHTR7 | |
| SCHEMBL29786225 | 0.69 | DRD2 (0.67) | GAAHTR1ADRD2HTR6DRD3 | |
| SCHEMBL1030637 | 0.69 | DRD2 (0.67) | GAAHTR1ADRD2HTR6DRD3 | |
| SCHEMBL27524294 | 0.68 | HPGD (0.49) | GAAPOLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7370433 | 0.68 | MAPK1 (0.49) | DRD2POLBHTR7DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |