Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324941 | 0.81 | — | — | |
| SCHEMBL18721774 | 0.71 | MAOA (0.46) | ALDH1A1HTTMAOAMAPTKDM4E | |
| SCHEMBL8487542 | 0.71 | MAOA (0.46) | ALDH1A1HTTMAOAMAPTKDM4E | |
| SCHEMBL15630156 | 0.69 | — | — | |
| SCHEMBL2691041 | 0.67 | — | — | |
| SCHEMBL60469 | 0.67 | ALDH1A1 (0.47) | ALDH1A1HTTMAOAMAPTKDM4E | |
| SCHEMBL11934162 | 0.67 | MAOA (0.43) | ALDH1A1HTTMAOAMAPTKDM4E | |
| SCHEMBL60468 | 0.67 | MAOA (0.43) | ALDH1A1HTTMAOAMAPTKDM4E | |
| SCHEMBL8083467 | 0.67 | ALDH1A1 (0.47) | ALDH1A1HTTMAOAMAPTKDM4E | |
| SCHEMBL1486117 | 0.65 | MAOA (0.41) | ALDH1A1HTTMAOAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032428-A2 | SYNTHESIS OF DIAMINES | INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY (IT) | 1999-07-01 | — | — | WO | disclosed |