Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191817 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL7323969 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL7323961 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL12870972 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL21786201 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL13840142 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL2324941 | 0.76 | — | — | |
| SCHEMBL17123005 | 0.75 | ALDH1A1 (0.31) | ALDH1A1MAPTKDM4E | |
| SCHEMBL14959874 | 0.75 | POLB (0.46) | ALDH1A1MAPTKDM4EPOLBMAOA | |
| SCHEMBL25139402 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270825-A1 | STAPLED OLEFIN CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS | MERCK SHARP & DOHME LLC (US) | 2023-08-31 | — | — | US | disclosed |
| WO-2021136808-A1 | CONJUGATES UNDERGOING INTRAMOLECULAR REARRANGEMENTS | ASCENDIS PHARMA A/S (DK) | 2021-07-08 | — | — | WO | disclosed |
| US-20140235446-A1 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-21 | — | — | US | disclosed |
| US-20140235446-A1 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-21 | — | — | US | disclosed |
| EP-2565205-A1 | GLUCAGON-LIKE PEPTIDE-1 ANALOGUE AND USE THEREOF | Zhejiang Beta Pharma Inc. (CN) | 2013-03-06 | — | — | EP | disclosed |
| US-8039532-B2 | Heterocyclic compound, ultraviolet absorbent and composition containing the same | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| EP-2223909-A1 | Process for preparing pentanoic diacid derivatives | Ratiopharm GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| US-20100210762-A1 | HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME | FUJIFILM CORPORATION (JP) | 2010-08-19 | — | — | US | disclosed |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| WO-2009027081-A2 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES | RATIOPHARM GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |
| US-20080234464-A1 | Compound Having Amino Acid Residue or Peptide Residue and Process for Producing the Same | CREDIA JAPAN CO., LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210762-A1 | HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME | F12, F2, CYP24A1 | ALDH1A1 1492/4885MAPT 4121/4885KDM4E 3903/4885 |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | SQOR, NQO1, PBRM1 | ALDH1A1 739/4885MAPT 3419/4885KDM4E 3362/4885 |
| US-20230270825-A1 | STAPLED OLEFIN CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS | GLP1R, GIPR, GCGR | ALDH1A1 2572/4885MAPT 3891/4885KDM4E 4100/4885 |
| US-20080234464-A1 | Compound Having Amino Acid Residue or Peptide Residue and Process for Producing the Same | NGLY1, ELOVL6, ELOVL1 | ALDH1A1 3518/4885MAPT 3234/4885KDM4E 1796/4885 |
| US-20140235446-A1 | 2,3-DIPHENYL-VALERONITRILE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | DDT, CYP1A1, CYP4Z1 | ALDH1A1 114/4885MAPT 4341/4885KDM4E 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.