Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11951301 | 0.79 | TSHR (0.30) | TSHRTHPO | |
| SCHEMBL5037124 | 0.77 | — | — | |
| SCHEMBL187536 | 0.76 | — | — | |
| SCHEMBL17772 | 0.73 | — | — | |
| SCHEMBL102146 | 0.73 | MMP1 (0.33) | MMP2MMP8 | |
| SCHEMBL5037125 | 0.73 | MMP1 (0.33) | MMP2MMP3MMP8 | |
| SCHEMBL3538407 | 0.73 | — | — | |
| SCHEMBL17106814 | 0.72 | MMP1 (0.31) | MMP2MMP3MMP8 | |
| SCHEMBL2110311 | 0.70 | MMP1 (0.36) | MMP2MMP3MMP8TSHR | |
| SCHEMBL20270690 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177647-A1 | FLUOROPOLYETHER GROUP-CONTAINING COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2022-06-09 | — | — | US | claimed |
| CN-108569969-A | A kind of synthetic method of 3-aminophenylacetylene | 西安格瑞德化工新材料有限公司 | 2018-09-25 | — | — | CN | claimed |
| WO-2014001527-A2 | LIPID ANALYSIS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2014-01-03 | — | — | WO | claimed |
| US-20240336594-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2024-10-10 | — | — | US | disclosed |
| US-20240239777-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |
| CN-118324846-A | Bufogargarizin A preparation method | 南方科技大学 | 2024-07-12 | — | — | CN | disclosed |
| US-20240226094-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KAWASAKI DISEASE | XU, Cong (CN) | 2024-07-11 | — | — | US | disclosed |
| US-20240228488-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-11 | — | — | US | disclosed |
| EP-4396187-A1 | NAPHTHYRIDINE COMPOUNDS AS INHIBITORS OF KRAS | Incyte Corporation (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024140704-A1 | PYRIDAZINE FUSED ARYL RING COMPOUND AND USE THEREOF | 正大天晴药业集团股份有限公司 | 2024-07-04 | — | — | WO | disclosed |
| US-6552239-B1 | Reacting ketophosphonate with diazo-transfer reagent generating a ketodiazophosphonate which is reacted with cyclopropanecarboxaldehyde | MERCK & CO., INC. | 2003-04-22 | — | — | US | disclosed |
| WO-2003031434-A1 | COMPOUNDS AND METHODS | SMITH KLINE BEECHAM CORPORATION (US) | 2003-04-17 | — | — | WO | disclosed |
| EP-1274424-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020156273-A1 | Streptogramin derivatives, their preparation and compositions which contain them | NOVEXEL (FR) | 2002-10-24 | — | — | US | disclosed |
| WO-2002081415-A2 | METHOD FOR INHIBITING METAP2 | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-17 | — | — | WO | disclosed |
| US-6458830-B1 | THE COMPOUNDS ARE OF PARTICULAR USE IN THE TREATMENT OR PREVENTION OF DEPRESSION, ANXIETY, PAIN, INFLAMMATION, MIGRAINE, EMESIS AND POSTHERPETIC NEURALGIA. | MERCK SHARP & DOHME LTD. | 2002-10-01 | — | — | US | disclosed |
| EP-1165540-A1 | TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001078723-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-2000056727-A1 | TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226094-A1 | ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KAWASAKI DISEASE | PHKA1, PHKA2, PHKG1 | MMP2 1725/4885MMP3 1691/4885MMP8 1812/4885 |
| US-20240336594-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | MALT1, CYP51A1, BCR | MMP2 3864/4885MMP3 3559/4885MMP8 4389/4885 |
| US-20240228488-A1 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | KLKB1, KLK5, KLK1 | MMP2 244/4885MMP3 271/4885MMP8 301/4885 |
| US-20020156273-A1 | Streptogramin derivatives, their preparation and compositions which contain them | MRPL21, SRI, STS | MMP2 379/4885MMP3 672/4885MMP8 939/4885 |
| US-20240239777-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | MMP2 1393/4885MMP3 831/4885MMP8 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.