Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28758145 | 1.00 | TSHR (0.82) | — | |
| Pyridine SCHEMBL9569818 | 0.96 | — | — | |
| Pyridine SCHEMBL51070 | 0.95 | — | — | |
| Pyridine SCHEMBL3113408 | 0.95 | TSHR (0.90) | — | |
| Pyridine SCHEMBL839151 | 0.95 | — | — | |
| Pyridine SCHEMBL18059958 | 0.95 | TSHR (0.90) | — | |
| Pyridine SCHEMBL11442039 | 0.95 | TSHR (0.90) | — | |
| Pyridine SCHEMBL45360 | 0.95 | — | — | |
| Pyridine SCHEMBL7628539 | 0.95 | TSHR (0.90) | — | |
| Pyridine SCHEMBL839150 | 0.95 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561943-A | Dydrogesterone intermediate impurity and preparation method thereof | 新疆特丰药业股份有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-116768961-A | Preparation method of fluocinolone acetonide | 津药药业股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-111995650-B | Synthesis method of testosterone alkyl acid | 浙江神洲药业有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-112796715-B | Ternary water-control gas production method suitable for loose sandstone gas reservoir | 东营明德石油科技有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-112796715-A | Ternary water-control gas production method suitable for loose sandstone gas reservoir | 东营明德石油科技有限公司 | 2021-05-14 | — | — | CN | claimed |
| CN-118561943-A | Dydrogesterone intermediate impurity and preparation method thereof | 新疆特丰药业股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118146286-A | Preparation method of dehydronandrolone acetate | 潘高峰 | 2024-06-07 | — | — | CN | disclosed |
| CN-116768961-A | Preparation method of fluocinolone acetonide | 津药药业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111995650-B | Synthesis method of testosterone alkyl acid | 浙江神洲药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116333026-A | Preparation method of dydrogesterone intermediate | 北京济美堂医药研究有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112796715-B | Ternary water-control gas production method suitable for loose sandstone gas reservoir | 东营明德石油科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112796715-A | Ternary water-control gas production method suitable for loose sandstone gas reservoir | 东营明德石油科技有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-1503793-A | N-substituted non-aryl-heterocyclic NMDA/NR2B antagonists | — | 2004-06-09 | — | — | CN | disclosed |
| CN-1104427-C | Tricyclic inhibitors of farnesyl protein transferase | SCHERING CORP (US) | 2003-04-02 | — | — | CN | disclosed |
| CN-1242773-A | Ticyclic carbapenem compound | GLAXO WELLCOME SPA (IT) | 2000-01-26 | — | — | CN | disclosed |
| CN-1237165-A | Tricyclic inhibitors of farnesyl protein transferase | SCHERING CORP (US) | 1999-12-01 | — | — | CN | disclosed |
| CN-1235597-A | Heterocycle derivatives inhibiting factor Xa | ZENECA LTD (GB) | 1999-11-17 | — | — | CN | disclosed |
| CN-1234801-A | 3-carboxamide derivatives of 5H-pyrrolo [2, 1-C ] [1,4] -benzodiazepine * | AMERICAN HOME PROD (US) | 1999-11-10 | — | — | CN | disclosed |
| CN-1231666-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1999-10-13 | — | — | CN | disclosed |
| US-5908929-A | Process for the manufacture of the antibiotic 7-(D-α-amino-α-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid (cephalexin) and pharmaceutically acceptable salts thereof | VITARA CHEMICALS LIMITED (IN) | 1999-06-01 | — | — | US | disclosed |