Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491351 | 0.83 | TRPA1 (0.43) | ATMMEN1KMT2AACHEALDH1A1 | |
| SCHEMBL3907273 | 0.74 | ACHE (0.54) | KMT2AACHEGAANFE2L2ALDH1A1 | |
| SCHEMBL5309973 | 0.74 | KMT2A (0.43) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL3818629 | 0.73 | MEN1 (0.37) | MEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL7148548 | 0.72 | NFE2L2 (0.44) | KMT2ANFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6707541 | 0.71 | ACHE (0.45) | ATMMEN1KMT2AACHEGAA | |
| SCHEMBL19752660 | 0.68 | GAA (0.47) | ATMMEN1KMT2AACHEGAA | |
| SCHEMBL27372250 | 0.67 | ACHE (0.68) | MEN1KMT2AACHEGAANFE2L2 | |
| SCHEMBL20868149 | 0.67 | ACHE (0.68) | MEN1KMT2AACHEGAANFE2L2 | |
| Formamide SCHEMBL28161394 | 0.67 | ACHE (0.68) | MEN1KMT2AACHEGAANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032482-A1 | HYPOGLYCEMIC IMIDAZOLINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |