Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 7/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486218 | 0.88 | MTNR1B (0.40) | MTNR1BMTNR1ASLC9A1PARP1ALOX5 | |
| SCHEMBL8484598 | 0.84 | MTNR1B (0.41) | MTNR1BMTNR1ASLC9A1PARP1MAOA | |
| SCHEMBL8489602 | 0.81 | MTNR1B (0.39) | MTNR1BMTNR1ASLC9A1PARP1 | |
| SCHEMBL8489828 | 0.76 | MGAM (0.46) | ALOX5 | |
| SCHEMBL8487685 | 0.76 | DRD2 (0.41) | MTNR1BMTNR1ASLC9A1ALOX5 | |
| SCHEMBL6677463 | 0.75 | MTNR1B (0.48) | MTNR1BMTNR1AMAOA | |
| SCHEMBL8489131 | 0.73 | SLC9A1 (0.37) | MTNR1BMTNR1ASLC9A1PARP1ALDH1A1 | |
| SCHEMBL6677849 | 0.72 | MTNR1B (0.67) | MTNR1BMTNR1A | |
| SCHEMBL8488073 | 0.72 | MTNR1B (0.41) | MTNR1BMTNR1ASLC9A1ALDH1A1MAPT | |
| SCHEMBL6677851 | 0.72 | MTNR1B (0.67) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |