Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488085 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1GAAMAPK1NPSR1 | |
| SCHEMBL8491739 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAMAPK1HPGD | |
| SCHEMBL8490031 | 0.69 | HTT (0.53) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8490034 | 0.69 | HTT (0.53) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7959569 | 0.68 | TSHR (0.40) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31454786 | 0.64 | MAPK9 (0.55) | GAAMAPK1HPGDHTTMAPT | |
| SCHEMBL15091787 | 0.64 | L3MBTL1 (0.65) | KDM4EALDH1A1GAAMAPK1NPSR1 | |
| SCHEMBL8486011 | 0.63 | RAB9A (0.44) | KDM4EKMT2A | |
| SCHEMBL18088844 | 0.63 | NPSR1 (0.55) | KDM4EALDH1A1GAAMAPK1NPSR1 | |
| SCHEMBL18076240 | 0.63 | NPSR1 (0.55) | KDM4EALDH1A1GAAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999038865-A1 | 8-AZABICYCLO(3.2.1)OCT-2-ENE DERIVATIVES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |