Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488359 | 0.89 | ALDH1A1 (0.37) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8496033 | 0.86 | KDM4E (0.35) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8493394 | 0.86 | NR1H4 (0.36) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8492757 | 0.85 | FTO (0.39) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8492065 | 0.84 | THRB (0.40) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8492238 | 0.83 | HPGD (0.33) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8488994 | 0.83 | MAPT (0.40) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8492682 | 0.83 | SMURF2 (0.40) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8491936 | 0.82 | NR1H4 (0.33) | KDM4EALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8491813 | 0.82 | HPGD (0.37) | ALDH1A1CYP11B1CYP11B2NR1H4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | claimed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |